The crushed leaves are also used to treat mild fevers, colds, rheumatism and snake bites, and as a. Leaves are subsessile or shortly petiolate, linear or linearly lanceolate, obtuse, pubescent up to 8. Leucas revealed the presence of tannins, alkaloids and glycosides ramya et al. In india and the philippines leucas aspera is very common weed. The present investigation was aimed at evaluating the ethanol extract of leaves of leucas aspera has been found to possess antibacterial activity and antiinflammatory activity, cyclooxygenase cox, also called prostaglandin h synthase or pghs is a bifunctional enzyme exhibiting both cyclooxygenase and peroxidase activities. In vitro studies on antibacterial, antifungal, and cytotoxic properties of leucas aspera m akter1, mai khan2, mda muhsin1, k hamid3, m obayed ullah4, ij bulbul5, a firoz 1, m burhan uddin, kf urmi1 1department of pharmacy, jahangirnagar university, dhaka, bangladesh. Lamiaceae is an important medicinal plant in indigenous systems of medicine in india and commonly known as thumbai. Methanolic extract of leucas aspera was evaluated, in vitro, for its ability to inhibit the major enzyme activities of naja naja venom including protease, phospholipase a 2, hyaluronidase and hemolytic factors. Leucas aspera is an annual plant that can reach heights of 1560 cm. Neuropharmacological profile of methanolic extract of leucas. Leucas aspera is known for its antiinflammatory, antithrombotic, antioxidant, anti carcinogenic properties 7 whereas cassia alata is known for its antifungal, laxative, purgative and antioxidant activity 11. Microbiological activities of volatile constituents of leucas aspera. Labiatae is a common aromatic herb and grows generously in south india and in the broad area of south asia.
Inhibition of naja naja venom enzymes by the methanolic. It is easy to id leucas when you have a live specimen with flower in hand otherwise it is difficult unless one worked on it. Leucas aspera is a plant species within the genus leucas and the family lamiaceae. The record derives from wcsp data supplied on 20120323 which reports it as an accepted name record 111632 with original publication details. It belongs to family labiatae and its scientific name is phlomis. Floral formula and floral diagram biology discussion. Green synthesis of silver nanoparticles using leucas aspera. Jun 30, 2015 the genus leucas includes about 100 asiatic and african species. Aqueous extract showed potent inhibitory activities against eac cells procreation in invivo. The present object focuses on phyto constituents and antiangiogenic activity of the leucas aspera leaves extract. In general, the crushed leaves of leucas species are applied to wounds, sores, especially those of the eyes and nose, chronic skin diseases, such as psoriasis and scabies. Leucas aspera material was collected from gangapur dam, nasik, maharashtra, india.
If the file has been modified from its original state, some details such as the timestamp may not fully reflect those of the original file. This study was aimed to develop an efficient protocol for micropropagation of leucas aspera using nodal explants. However, the name labiatae is also exempted and conserved under nomina conservanda because of their constant use for a long time. In this formula k represents calyx, ccorolla, p perianth, aandroccium, ggynoecium. Antioxidant, antibacterial and cytotoxic effects of the. Thin layer chromatographic investigation on leave of. Medicinally, it has antimicrobial, insecticidal, fever reducing, larvicidal and inflammation reducing properties. Leucas aspera is widely use d as foods and also for nutr itional requirement in countryside which was reported to have high protein content of 21. Phytochemical evaluation and in vitro antioxidant activity of. Narasimhan, centre for floristic research, department of botany, madras christian college, tambaram. The synthesized nanoparticles were characterized by using uv. Traditionally, this species is taken orally for analgesic, antiinflammatory, antibacterial and wound healing treatments.
Department of pharmacy, international islamic university chittagong, chittagong4203, bangladesh. In thin layer chromatography tlc, a liquid the mobile phase is allowed to migrate across a solid stationary phase15. Acetone extracts of leucas aspera roots showed excellent antibacterial activity against the tested bacterial strains. Leucas aspera at gandipet, hyderabad, ap w2 img 9054. Link lamiaceae is an annual, branched herb used in traditional medicine as an antipyretic and insecticide. Antifungal susceptibilities of certain clinically isolated dermatophytes to methanol extracts of leucas aspera and leucas zeylanica leaves were performed using agar well diffusion method. Lamiaceae herb rainy 23 gamhair pump, gamhair gmelina arborea roxb. Antioxidant and antibacterial activity of different parts of leucas aspera. Specifically, we assessed the improved anticancer activity of leucas aspera nanoparticles compared with methanolic crude extract in pc3 prostate cancer cells and normal cells.
The aim of the present study is to probe the antimicrobial activities of methanol leaf extract of leucas sp. Pdf two novel phytotoxic substances from leucas aspera. Home free radicals and antioxidants, vol 7, issue 2, juldec, 2017 phytochemical evaluation and in vitro antioxidant activity of various solvent extracts of leucas aspera willd. Leucas aspera is used by rural and tribal population in assam in various problems like dysentery, diarrhea, sinusitis, headache, tonsil etc 814. The genus leucas includes about 100 asiatic and african species. For more multimedia, look at leucas aspera on wikimedia commons. Calyx tubular to obconical, rarely dilated, 10veined, straight or curved, truncate or oblique at throat. Different parts of this plant root, flower, leaf, stem have been found to have antioxidant, antibacterial and cytotoxic effect. The plant is widely found in bangladesh and its bengali name is dondokolos. Leucas aspera was tested for its prostaglandin pg inhibitory and antioxidant activities. The record derives from wcsp which reports it as an accepted name record 111632 with original publication details. Bioactive components have been isolated such as lignin,flavonoids, coumarins, steroids, terpenes, fatty acids, and aliphatic longchain compounds. Although the species has many different common names depending on the region in which it is located, it is most commonly known as thumbai or thumba.
Verticillasters few to many flowered, widely spaced, uniform or reduced in size at end of branches. Apr 17, 2020 a few uploads earlier identified as leucas cephalotes anti bacterial activity of leucas aspera leaf extract against micrococcus pyogenes and escheria coli have also been reported rastogi and mehrotra details of some important contributors. Pdf leucas aspera commonly known as thumbai is distributed throughout india from the himalayas down to ceylon. The present finding suggests that the methanol root extract of l. It is annulate in the middle portion and pubescent on the upper region. Both the extracts exhibited significant antiinflammatory action of acute and chronic inflammation. Phytochemical evaluation and in vitro antioxidant activity.
The type of phytochemicals present in the extract was analyzed. Leucas aspera belongs to the family lamiaceae commonly known. Leucas aspera lamiaceae, an aromatic herbaceous plant, is well known for many medicinal properties and a number of bioactive compounds against animal cells have been isolated. Leucas aspera is typically found in dry, open, sandy soil and is abundant in areas with waste. Investigation of the inhibitory fraction of leucas aspera on prostaglandininduced contraction in guinea pig ileum provided four new diterpenes, leucasperones a 1 and b 2 and leucasperols a 3 and b 4, and three new isopimarane glycosides, leucasperosides a, b, and c 5. Inhibition of cox2 enzyme by the various extracts of leucas. This file contains additional information such as exif metadata which may have been added by the digital camera, scanner, or software program used to create or digitize it. Leucas aspera a perfect poor man remedy journal of. Bioactive components have been isolated such as lignin,flavonoids, coumarins, steroids.
In this work deals with the synthesis and characterization of silver nanoparticles using leucas aspera flower. Leucas aspera is one of the herbs found momentous due to its overriding medicinal outcomes. Molecular docking studies of phytochemicals from leucas aspera targeting escherichia coli and bacillus subtilis subcellular proteins. The relative density of most of weeds in cultivated fields the relative density of most of weeds in cultivated fields were 2. Leucas aspera nanomedicine shows superior toxicity and cell. Tlc is a good technique to analyze the compound of a. The hydrodistilled essential oil was obtained from the aerial parts of l. Plant tissue culture has paved way for the production of both pathogenfree plants and secondary metabolites in large scale. Diterpenes from leucas aspera inhibiting prostaglandin.
Using the patented highspeed transfer technology in ibm aspera, national instruments corporation was able to significantly accelerate its global software development pipeline by synchronizing large software builds between teams at 17 sites around the world from its centralized data center in austin, texas. Leucas aspera is a plant which is seen on waste land and roadsides of india. The purpose of this present study was to investigate the central nervous system cns depressant activities of methanolic extract of. Link is an accepted name this name is the accepted name of a species in the genus leucas family lamiaceae. The result obtained shows that all the extracts expressed remarkable antifungal activity. Phytochemical and pharmacological investigation of an indigenous medicinal plant leucas aspera v. The plants have been reported to have antiinflammatory, analgesic, antidiarrheal, antimicrobial, antioxidant, and insecticidal activities. The below mentioned article provides a study note on the floral formula and the floral diagram. Phytol a chemical constituent of leucas aspera through. All structured data from the file and property namespaces is available under the creative commons cc0 license. Leucas aspera commonly known as thumbai has a wide variety of medical applications.
Caryophyllene and 1octen3ol chemotypes, journal of chromatographic science on deepdyve, the largest online rental service for scholarly research with thousands of academic publications available at your fingertips. Plant details information about leucas aspera plant. In vitro studies on antibacterial, antifungal, and. Leucas aspera family labiatae is an annual herb found throughout india as a weed in cultivated fields, wastelands and roadsides. The decoction of whole plant is used for curing fever. Lamiaceae labiatae according to the rules of icbn the names of the families should end in aceae. There is an increasing commercial demand for nanoparticles due to their wide applicability in various areas such as electronics, catalysis, chemistry, energy, and medicine. If the file has been modified from its original state, some details such as the timestamp may not. Molecular docking studies of phytochemicals from leucas. Neuropharmacological profile of methanolic extract of. General information leucas aspera is an erect, annual plant with a muchbranched stem 30 60cm tall. Files are available under licenses specified on their description page. Home free radicals and antioxidants, vol 7, issue 2, juldec, 2017 phytochemical evaluation and in vitro antioxidant activity of various solvent extracts of leucas aspera. Verbenaceae tree spring 24 guma arxa, choti guma leucas cephalotes spreng.
The juice of the leaves is used as remedies for psoriasis, chronic. Leucas aspera nanomedicine shows superior toxicity and. Leucas aspera is commonly found throughout india and the philippines as well as the plains of mauritius and java. Jul 09, 2019 antimicrobial activity of leucas aspera pdf both the extracts exhibited a significant antibacterial activity against all the screened microorganisms. Thus the new name for the family labiatae became lamiaceae. Phytochemical and pharmacological investigation of an. Then the remaining marc was successively extracted with ethyl. Pharmacological and medicinal uses of achyranthes aspera 127 bronchoprotective activity. Jcprc5 222 phytochemical studies on leucas aspera latha.
An update of leucas aspera a medicinal plant international. Home pharmacogn j, vol 11, issue 2, marapr, 2019 molecular docking studies of phytochemicals from leucas aspera targeting escherichia coli and bacillus subtilis subcellular proteins. Leucas is a genus of plants in the family lamiaceae, first described by robert brown in 1810. Calyx tubular to obconical, rarely dilated, 10veined, straight or curved, truncate or oblique at throat, projected. Devi rajeswari department of biomedical sciences, school of biosciences and technology, vit university, vellore 14, tamilnadu, india. A total of species belo hedge leucas capitata desf. Antiangiogenic and proapoptotic activity of aqueous extract. The leaves of the leucas aspera are linear, obtuse and are petiolate.
The healing properties of plants has been transferred within the human communities for over the centuries. Antimicrobial activity of leucas aspera pdf both the extracts exhibited a significant antibacterial activity against all the screened microorganisms. The aqueous and alcoholic extracts of leucas aspera were investigated for their action on experimental inflammation and on mast cell degranuatlion. Leucas aspera at gandipet, hyderabad, ap w img 9054. The plant is used to treat many diseases such as cough,cold diarrhea,inflammatory diseases. In vitro studies on antibacterial, antifungal, and cytotoxic. The plant is used for the treatments of antipyretic, antirheumatic, antiinflammatory, and antibacterial diseases. Leucas aspera lamiaceae leucas leuca white may represent the colour of the flower aspera rough surface texture of the leaf. Habitat and ecology leucas aspera is typically found in dry, open, sandy soil and is abundant in areas with waste 2. It contains over 200 species, widespread over much of africa, and southern and eastern asia iran, india, china, japan, indonesia, etc. Academic sciences asian journal of pharmaceutical and.
Leucas aspera commonly known as thumbai, gumma is found all over india. This file is licensed under the creative commons attributionshare alike 4. Although dronpushpi is a problematic weed for farmers, it is a tasty potherb for many rural people and a valuable medicinal herb for herbalists and is cultivated for. The relative density of weeds of cultivated fields were0. Leucas aspera consists of phyto constituents which include.
Department of agriculture agricultural research service. In vitro micropropagation and comparative free radical. According to the rules of icbn the names of the families should end in aceae. Ethanolic extract of achyranthes aspera shows bronchoprotective effect in toluene diisocyanate tdi induced occupational asthma in wistar rats as reported by goyal et al. In the present study, the antioxidant property of ethanolic extract of leucas aspera has been investigated. In this study, the whole plant of leucas aspera was first defatted with hexane and discarded. It is sometimes found convenient to describe a flower by a simple and concise formula known as the floral formula.
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